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How do I Request Specimen from the AIDS and Cancer Specimen Resource?
The AIDS and Cancer Specimen Resource Steering Committee solicits Letters of Intent (LOI) from investigators throughout the year with a minimum of paper work. The application process is simple and straightforward. Go to LOI forms to download.
1. Submit a LOI to the National Cancer Institute Program Director. This LOI is to tell us about your research plan as well as the number and type of specimen required. LOIs are accepted year round.
2.The LOIs are reviewed by an Independent Research Evaluation and Decision Panel (REDP) composed of experts in various fields. A priority score is attached and forwarded to the ACSR Central Operations and Data Coordinating Office to ensure that the specimen are available and to assign an ACSR representative to assist with any scientific issues raised by the REDP.
3.The ACSR Executive Steering Committee makes the final decision on providing the specimens and data. If the ACSR cannot meet your needs, we will attempt to identify an appropriate resource.
Factors influencing LOI priority scores:

  • Scientific merit of the application
  • Experience of the investigator
  • Statistical validity of the study
  • Valid specimen size requested to accomplish study
If the specimens requested are available, the LOIs with the highest priority score are sent a letter of approval with a commitment from the ACSR to provide the necessary specimens once funding of the study has been confirmed. This letter of approval may be incorporated into NIH or other grant applications. The investigator must have IRB approval.
After notification is received by the ACSR Central Operations and Data Coordinating Office that funding has been secured; specimens are released to the investigator. Investigators who fail to obtain funding within six months of receiving their letter of approval will have the approval voided and those specimens will become available to other investigators.
If LOIs are not approved the investigator will be provided with a letter stating the concerns of the REDP and/or the ACSR Executive Steering Committee. The ACSR representative will work with the investigator to resolve any remaining scientific issues so the LOI may be resubmitted in a timely manner.