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The East Coast AIDS and Cancer Specimen Resource (EC ACSR) was established by the National Cancer Institute as part of the national
AIDS and Cancer Specimen Resource (ACSR) in 1994. The goal of the bank is to collect, preserve, and maintain a comprehensive,
confidential, state-of-the-art bank of malignant and other specimens and clinical data from HIV-infected individuals for national
research. The specimens for the EC ACSR are maintained within the Department of Pathology at the George Washington University Medical
Center (GWUMC). |
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ACSR Mid-Region Site - Ohio State
University administers the Mid-Region of ACSR Program. Affiliates include Emory University, Rush University, University of Texas Southwestern, and Vanderbilt University. |
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NATIONAL
CANCER INSTITUTE - The National Cancer Institute (NCI) is a component
of the National Health Institutes and the Federal Government’s primary agency
for cancer research and training. The NCI coordinates the National Cancer
Program, which conducts and supports research, training, health information
dissemination, and other programs with respect to the cause, diagnosis,
prevention, and treatment of cancer, rehabilitation from cancer, and the
continuing care of cancer patients and their families. |
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The NCI Clinical Trials Cooperative Groups have banked tumor specimens
from large numbers of uniformly treated cancer patients with a variety of
malignancies. Each group has a review process for research proposals. If
proposals receive favorable reviews, specimens with clinical, treatment and
outcome data can be made available to researchers through collaborative
arrangements. These banked specimens are most useful for clinical correlative
studies on uniformly treated patient populations. Contact the
NCI Specimen Resource Locator website or the NCI Tissue Expediter,
(301) 496-7147; e-mail: tissexp@mail.nih.gov.
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The
NCI Cooperative Breast Cancer Tissue Resource (CBCTR) can provide
researchers with access to approximately 9,000 cases of formalin-fixed,
paraffin-embedded primary breast cancer tissue, with associated pathology and
clinical data. The collection is particularly well-suited for validation
studies of diagnostic and prognostic markers. Contact
CBCTR's website or Ms. Sherrill Long, Information Management Services,
Inc., (301) 984-3445; e-mail: longs@imsweb.com.
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The
NCI Cooperative Human Tissue Network (CHTN) provides normal, benign,
pre-cancerous and cancerous human tissue to the scientific community for basic
and developmental studies in many areas of cancer research. Contact the
CHTN website or 1-866-GO2-CHTN (1-866-462-2486)
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The NCI Specimen Resource Locator is a database that helps researchers
locate specimens for research. The database includes resources such as tissue
banks and tissue procurement systems with access to normal, benign,
pre-cancerous and/or cancerous human tissue covering a wide variety of organ
sites. Researchers specify the types of specimens, number of cases,
preservation methods and associated data they require. The Locator will search
the database and return a list of tissue resources most likely to meet the
requirements. When no match is obtained, the researcher is referred to the NCI
Tissue Expediter (e-mail: tissexp@mail.nih.gov).
The Tissue Expediter is a scientist who helps match researchers with
appropriate resources or identify appropriate collaborators when those are
necessary. |
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The Manhattan HIV Brain Bank (MHBB) is a
research resource (R24 award) funded by the National Institute of Mental Health. Due to the advanced
nature of its cohort, patients with a variety of neoplasms have been enrolled, including those with
central nervous system lymphomas. Most current holdings are in the form of fixed, embedded tissues
that can be sectioned and assembled into microarrays; frozen tissues and fluids are being collected
prospectively. Inventories will be listed through the ACSR. |
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The NIH AIDS Reagent Program evolved from a small bank of HIV research materials
into a unique worldwide resource of state-of-the art reagents for HIV and other
pathogens. Many of these reagents are not commercially available. The first
Catalog, published in 1988, listed 62 reagents from 20 contributors. The NIH
AIDS Reagent Program has grown significantly during the past sixteen years, and
it now has over 5,200 reagents for public distribution. Reagents are
shipped to scientists all over the world. The value of the NIH AIDS Reagent
Program is evident from the diversity of registered users; as of June 2003,
scientists from the US and 65 foreign countries registered to receive reagents.
During the past year over 14,000 reagents were provided. US scientists obtaining
AIDS reagents from the program work primarily in academ-ic settings. There are
also users from industry and the Federal Government. |
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AIDS
MALIGNANCY CONSORTIUM (AMC) - The AIDS Malignancy Consortium (AMC) is a
NCI-supported clinical trials group, founded in 1995 to support innovative
trials for AIDS-associated malignancies. The AMC is committed to enhancing
therapeutic options for patients with AIDS-associated malignancies. |
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AIDS
ReSearch Alliance - is a community-based non-profit HIV/AIDS research
facility in West Hollywood CA, conducting clinical trials and basic research of
promising new therapies for HIV disease. For more information, visit their site
at http://www.aidsresearch.org,
call 310.358.2423, or contact
info@aidsresearch.org. |
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The Cancer
Family Registries (CFRs) include two international registries: the
Cancer Family Registry for Breast Cancer Studies (Breast CFR) and the Cancer
Family Registry for Colorectal Cancer Studies (Colon CFR). The Breast CFR
provides family history information, biological specimens and epidemiologic and
clinical data from clinic-based and population-based families at risk for
breast and ovarian cancers. The Breast CFR infrastructure is particularly
suited to support interdisciplinary and translational breast cancer research.
Similarly, the Colon CFR collection includes family history information,
epidemiologic and clinical data, and related biological specimens from
individuals with colorectal cancer and their families. The colon CFR is a
resource for population and clinic-based, translational research in the genetic
epidemiology of colorectal cancer. For information on these registries, contact
the CFR website or Dr. Daniela Seminara, NCI, (301) 496-9600; e-mail:
seminard@mail.nci.nih.gov. |
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Cell Technology, Inc (CTI)
is a woman-owned small business in the Baltimore-Washington
Metropolitan area and it is an institutional level member of the
International Society for Biological and Environmental Repositories (ISBER).
CTI provides repository services for the storage and distribution
of Biological materials in a secure and controlled environment.
Following facilities are currently available at the CTI Repository:
Equipment for the Storage of Biological Materials,
Computerized Temperature Monitoring System,
Back-up Power Generator,
Controlled access to the storage area, and
Computerized Inventory Control System. |
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HIV InSite is a university-based, global Internet resource on
HIV/AIDS that incorporates comprehensive, multidisciplinary information on basic science, treatment, prevention, and policy, and is one of the world’s most visited HIV/AIDS Web sites.
HIV InSite is part of the University of California San Francisco’s Center
for HIV Information (CHI), whose mission is to advance the prevention and
care of HIV infection and related illnesses worldwide through the
development, organization, and dissemination of expert knowledge.
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The University of
California San Francisco-Gladstone Institute of Virology and Immunology Center
for AIDS Research (CFAR) seeks to enhance and expand collaborative,
multidisciplinary HIV research occurring at the intersections of the basic,
clinical and behavioral/epidemiological scientific disciplines. |
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